University of Massachussetts Amherst, USA
University of Massachusetts Amherst
Dr. Ma studies genome evolution combining theoretical, computational and experimental approaches. Her lab focuses on a model system Fusarium oxysporum, a highly adaptive species complex causing destructive and intractable wilt diseases across a broad spectrum of plant hosts. The Fusarium comparative genomics demonstrates that horizontal transfer of entire chromosomes conveys pathogenicity and contributes directly to the niche adaptation. This discovery establishes F. oxysporum as an effective model to investigate horizontal transfer in eukaryotes, and the pathogenicity chromosomes provide a focal point to investigate the genetic mechanisms that underlie pathogenesis against different plant hosts.
Web persona/lab page: www.umass.edu/biochem/faculty/li-jun-ma